Clinical Hepatocyte Transplantation (ARGH)-Juniper Publishers

 

JUNIPER PUBLISHERS-ADVANCED RESEARCH IN GASTROENTEROLOGY & HEPATOLOGY

 

 

CLINICAL HEPATOCYTE TRANSPLANTATION

Authored by Toshio Miki

A severe shortage of suitable allograft is a long-standing and worldwide problem for the patients who are waiting for organ transplantation. Hepatocyte transplantation has been proposed as an alternative therapeutic approach for liver disease patients to address these urgent and unmet medical needs. The cell replacement approach does not replace the orthotopic liver transplantation (OLT), but rather complement OLT especially for the patients who are not required whole liver replacement such as congenital metabolic disorders. This review article summarizes current knowledge and limitations of clinical hepatocyte transplantation and aims to advance our understanding towards the goal of developing novel cell replacement therapies for the patients who are on the OLT waiting list.

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Patterns of Exploratory /Locomotor Behaviour in Mice Following Chronic Consumption of Uncooked Beans

Authored by Aduema W

The effects of chronic consumption of uncooked beans diet on exploratory/locomotor behaviour were investigated. Thirty (30) CD1 mice weighing 18-35g were randomly assigned into three groups, viz; control, uncooked beans diet (50% w/w), while another set of mice were placed on serotonin precursor (5-HTP) diet (0.2mg/50g w/w) respectively for thirty days. All the mice had access to clean drinking water ad libitum. Before the neurobehavioral parameters were assessed, the phytochemical analysis of the beans, LD50 of the beans) and that of the serotonin precursor (5-HTP) were determined. Serotonin concentration was measured in the beans using gas chromatography analysis. The open field maze and light and dark transition box were employed for the evaluation of exploratory/locomotor behaviour. Daily food intake, water intake and body weight change were measured. The frequency of rearing in the open field was not significantly different in the uncooked beans and serotonin precursor fed group compared to control. However, the frequency of line crosses, stretch attend posture were decreased in the test group (p<0.05) compared to control. This indicates a decreased exploratory/locomotor behaviour in the test group.

To Read More... Fulltext in Advances in Biotechnology and Microbiology in Juniper Publishers

Medicine's "Future": Pilot Data from a US Sample Shows Surgeons More Likely to Encourage Children to Pursue Medicine

Authored by Irene Dimitriadis

A survey was conducted to ascertain knowledge on when doctors start having children and the likelihood of them encouraging their children to follow in their footsteps. Across all training levels, surgical specialties are more likely to encourage their children to become physicians compared to non-surgical specialties (64.3% vs 45.5%; p<0.0001, respectively). Amongst physicians with sons and daughters, 21.2% of responders report a gender bias in regards to encouraging their children to become doctors, of which almost twice as many parents report that they would encourage their son compared to their daughter to pursue medicine (14% vs 7.2%, p=0.08).

To Read More... Fulltext in Journal of Gynecology and Women’s Health in Juniper Publishers

The Metaphor of Cultural Entanglement in Northeast African Archaeology-Juniper Publishers

The Metaphor of Cultural Entanglement in Northeast African Archaeology

Authored by Julia Budka

Archaeology in Northeast Africa has long been dominated by ancient Egypt and its rich cultural heritage. The monuments located in modern Sudan, ancient Nubia, were first described and analyzed by Egyptologists and traditionally viewed from an "Egyptian" perspective, resulting in several shortcomings in assessing African indigenous cultures. Many studies exhibit an Egypt centric bias and are referring primarily to written Egyptian sources which have been read as accurate evidence, partly neglecting archaeological findings.

To Read More.... Fulltext in Global Journal of Archaeology & Anthropology in Juniper Publishers

Prerequisites for the Application of Low - Intensity Irrigation Systems on Sloping Lands as A Means to Combat Erosion in Azerbaijan

Authored by RAE ZH Aliyev*

The article examines the issues of studying the world experience and the results of many years of experiments in various countries on the applicability of low-intensity irrigation systems in various climatic and soil conditions shows that the creation of irrigation systems of this type is an effective and economically viable irrigation of various types of crops: perennial plantings, orchards, vineyards, forest plantations, shrub farms as soil protection means, grain-legumes, vegetables, ridge crops and technical crops, ornamental plantations, goons, nurseries and others. The low-intensity system (drip irrigation, micro sprinkling, aerosol irrigation, subsoil and inektsionnoy irrigation, etc. which has almost universal application, in particular, it is applicable where the use of other methods irrigation is impossible or ineffective.

To Read More.... Fulltext in Trend in Technical & Scientific Research in Juniper Publishers

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Recent Trends in Global Climate Warming with a Focus on Europe- Juniper Publisher

Juniper publishers- Open access journal of Oceanography and Fisheries

Authored by Martin T Dokulil

Even if the debate on whether we have reached a new epoch, the Anthropocene [1,2] or not, there is no doubt that humanity's impact on Earth has become extremely profound. The new epoch has perhaps begun at about 1950 as a result of economic growth and the resulting accelerating impacts, speeding up climate change [3,4]. Although many in the world are still sceptical about the relative impacts of human-induced climate change and natural climate variability [5], warming nevertheless continues to rise. The recent status of global warming will be described and discussed below.

To Read More.... Fulltext in Oceanography and Fisheries Open access journal in Juniper Publishers

Fluid Shear Stress Inhibits Differentiation of Growth Plate Chondrocytes, Partially Via Integrin Beta 1

Authored by Barbara D Boyan

Mechanical stimuli such as fluid shear stress contribute to cartilage homeostasis and serve as important parameters for tissue engineering bioreactors. While mechanical forces on articular chondrocytes are widely investigated, the objective of this study was to determine the effects of fluid shear stress on growth plate cartilage cells. Rat costochondral resting zone chondrocytes (RC) and chondrogenic ATDC5 cells were subjected to 0, 2, 3.5, 5, or 6.5 dynes/cm2 fluid shear stress in a cone-plate viscometer device for 24 hours, and thenwereharvested immediately or after an additional static culture period. Shear stress exposure decreased [35S]-sulfate and [3H]-thymidine incorporation, but these were partially or fully recovered to control levels following a 24-hour, post-shear static culture across shear treatments. Alkaline phosphatase activity was also dose-dependently lowered by shear at this interval.

To Read More.... Fulltext in Current Trends in Biomedical Engineering & Biosciences in Juniper Publishers

Corn Yield as Altered by Using On-Farm Seed Priming, Different Nitrogen Levels and Soil Moisture Regimes | Juniper Publishers

Corn Yield as Altered by Using On-Farm Seed Priming, Different Nitrogen Levels and Soil Moisture Regimes

Authored by Kamil Sardar

The experiment was conducted at New Developmental Farm, of The University of Agriculture Peshawar during summer 2013 to study the effect of seed priming, nitrogen (N) levels and soil moisture regimes on the yield and yield components of maize. Two separate experiments were conducted in RCB design, one under high moisture condition other under low moisture condition. Treatment combination of seed priming and N levels were kept in. Sub plots while moisture in main plots. Nitrogen was applied at (0, 75, 150kg N ha-1) in three split doses. Seed priming was consisted of dry seed, water soaked and seed primed in 0.2% Phosphorus (P) solution. Days to emergence and Emergence m-2 of maize were significantly affected by moisture and seed priming while N effect was not significant. Low moisture plots resulted in higher days to emergence as compared to high moisture plots. Higher days to emergence were recorded for dry seed as compared to P primed seed and water soaked seed.

To Read More..... Fulltext in Agricultural Research & Technology: Open Access Journal in Juniper Publishers

A Case Report and Review of the Literature

Authored by Rosario Fernandez Salmerón

Dermatomyositis (DM) is a rare paraneoplasic neurological syndrome (PNS) that may precedes the development of malignancies. It´s an uncommon inflammatory myophaty with characteristic cutaneous manifestations. The association between DM and cancer has long been recognized but is becoming more clearly delineated. Several studies have documented an increased rate of malignant disease associated with DM over that observed in the general population. The incidence of ovarian cancer developing in the setting of DM was reported to be as high as 13.3 % in one series.

To Read More.... Fulltext in Journal of Gynecology and Women’s Health in Juniper Publishers

Mesenchymal Stem Cells Markers

Authored by Vasiliki E Kalodimou

In the field of regenerative medicine, basic research and preclinical studies have been conducted to overcome clinical shortcomings with the use of stem cells, mesenchymal stem cells and adipose stem cells. They are present in adult tissues, including bone marrow, umbilical cord, umbilical cord blood and adipose tissue [1]. For many years, bone marrow-derived stem cells were the primary source of stem cells for tissue engineering applications. Russian-born Alexander A. Maximow in 1924 used extensive histological findings to identify a kind of spherical precursor cell in the mesenchyme, which can grow and differentiate into Different cell types. In late 1960’s the scientists Ernest A. McCulloch and James E. Till reveal for the first time the clonal nature of bone marrow cells.

To Read More.... Fulltext in Open Access Journal of Neurology & Neurosurgery in Juniper Publishers