Tuesday, November 27, 2018

Embryo Transfer in Upper Uterine Cavity versus Mid-Uterine Cavity in Cases of Previous Failed Implantation

Authored by Abdel-Rahman Anbar

The aim of this work is to compare site of embryo transfer in mid-uterine cavity versus site of embryo transfer in upper uterine cavity in cases of previous failed implantation following ICSI treatment protocol. A prospective study. Setting: private IVF center (walad and bent). Patients and methods: Sixty two infertile women undergoing ICSI, were recruited from Assisted Reproductive Technology Unit (ART hospital department), during the period between December 2015 to October 2017.

Anti-Apoptotic Effect of Semelil on Testicular Germ Cells in Streptozotocin-lnduced Chronic Diabetic Rats

Authored by Maryam Anjomshoa

It is well known that diabetes is associated with impairment of testicular function. The present study aimed to investigate the effect of Semilil, an herbal medicine with angiogenic action, on testicular germ cell apoptosis in streptozotocin (STZ)-induced chronic diabetic rats. Adult Male sprague dawley rats were divided into 5 groups: (1) diabetic group, (2) Semilil-treated diabetic group, (3) insulin- treated diabetic group, (4) Semilil plus insulin-treated diabetic group, and (5) control group. Semilil was administered intraperitoneally at the dose of 13mg/kg for 49 days. Apoptosis in testicular germ cells was determined by terminal-deoxynucleotidyl-transferase-mediated dUTP nick end labeling (TUNEL) staining. Apoptosis indices in testicular germ cells of animals were computed using the stereologic method.

Nongenomic Effect of T3 on the Na, K-ATPase Activity of Syncytiotrophoblast from Human Term Placenta

Authored by Fulgencio Proverbio

Several ion transport enzymes are positively regulated by genomic mechanisms, through the thyroid hormones T3 and T4. However, there is evidence indicating that these hormones might also exert non genomic effects on different transporting enzymes. A normal activity of the Na, K-ATPase of  syncytiotrophoblast is essential for ion homeostasis in this tissue, as well as for the growth and development of the fetus. In the current work it was studied the non genomic effect of thyroid hormones on the Na, K-ATPase activity of syncytiotrophoblast. The study was carried-out by incubating human term placental explants in the absence and presence of 10nMT3or 350nMT4 and then isolating the syncytiotrophoblast plasma membranes and assaying them for Na, K-ATPase activity. The enzyme activity was also assayed for freshly prepared plasma membranes in the presence of (0-15)nMT3 or (0-500)nMT4.

Changing Attitudes towards Assisted Reproduction and IVF

Authored by Kelly Oliver

If not so long ago pregnancy was something to be hidden, a private matter that required modesty in dress and behavior, now with sexy pregnant bodies and protruding baby bumps on the covers of tabloids every week, a new stigma is attached to Assisted Reproductive Technologies (ART), In Vitro Fertilization (IVF) and what goes on at fertility clinics, which is often showed in secrets. If a few decades ago a woman's pregnant body was considered obscene insofar as it was associated with sex—it was proof that she had sex--today the disconnect between sex and pregnancy made possible by new reproductive technologies appears as the new obscenity.

Semenoma Originated from an Ectopic Testis

Authored by Otheman Fahs

The authors report an observation of a meta static seminoma on an ectopic testicle in a 23 years old patient and discuss the epidemiological, diagnostic, therapeutic and evolutionary aspects of this entity. Clinical diagnosis is often difficult due to the diversity of clinical symptoms, the use of imaging, biological markers and percutaneous biopsyis essential to make the diagnosis. The anatomopathology and therapeutic aspects are similar to the testis in normal situations. Early diagnosis of these tumors involves the lowering of the cryptorchid testicles, because even if this lowering does not prevent the setumors, it allows better monitoring.

Monday, November 26, 2018

Be Wary of Using Poisson Regression to Estimate Risk and Relative Risk

Authored By  Leigh Blizzard
Fitting a log binomial model to binary outcome data makes it possible to estimate risk and relative risk for follow-up data, and prevalence and prevalence ratios for cross-sectional data. However, the fitting algorithm may fail to converge when the maximum likelihood solution is on the boundary of the allowable parameter space. Some authorities recommend switching to Poisson regression with robust standard errors to approximate the coefficients of the log binomial model in those circumstances. This solves the problem of non-convergence, but results in errors in the coefficient estimates that may be substantial particularly when the maximum fitted value is large. The paradox is that the circumstances in which the modified Poisson approach is needed to overcome estimation problems are the same circumstances when the error in using it is greatest. We recommend that practitioners should be wary of using modified Poisson regression to approximate risk and relative risk.


On Quantum 3-Pass Protocol

Authored By Ahmed E
Some proposed 3-pass protocols in quantum cryptography assumes that the qbits are 2-component. Here we propose a protocol without this assumption


Confidence Intervals for the Relative Risk

Authored by Michail Tsagris
Confidence interval for the ratio of two independent binomial proportions is an important measure, especially in medicine. The relative risk is such an example where accurate interval estimation is crucial. In this work we compare 4 different methods for the construction of such intervals. Simulation studies using many combinations of the sample sizes and of the true proportions reveal interesting conclusions as to the suitability of either method.


Relationship of Gelatynase B Enzyme Activity and Coronary Artery Disease

Authored by Aysegul Bayramoglu

Matrix metalloproteinases (MMPs) play an important role in the pathogenesis of atherosclerosis, the pathology underlying the majority of coronary artery disease (CAD). We planned to investigate the association of enzyme activities of gelatinase B (or matrix metalloproteinase-9) in CAD patients. For this reason,102 patients with CAD and 99 control group recruited in this study. Serum gelatinase B enzyme level determinated from these peripheral blood samples by using Enzyme-Linked Immunosorbent Assay (ELISA). The results were evaluated by using statistical analyses. The level of gelatinase B increased in patients according to control group. As a result of our study, serum gelatinase B level was associated with CAD and could be used as a clinical marker.

To read more.... Fulltext in Biostatistics and Biometrics Open Access Journal in Juniper publishers


Book Review ‘Rahsia Dan Imej Wanita’ (Malay Version)
Authored By Uqbah Iqbal
Written by Ghafar Nin and Merina Haji Ibrahim, this book states that a healthy body is a requirement for active women.The creators of the comet have long been utilizing natural plants for body care. 


Review Article on Impact of ATM Service on Customer Satisfaction Authored by Benyam Tadesse In banking industry, e-services ar...