Just Sayin’-Juniper Publishers

Just Sayin’... by Johann Hari in Global Journal of Addiction & Rehabilitation Medicine - Juniper Publishers

It is clear that Hari is speaking here not just of intimate human bonds of attachment and affection, although these are central to his argument. People are also connected to one another, to their society, to families, neighborhoods, organizations, to their nation, to a sense of meaning and purpose, to a higher calling and sense of how they “fit” in the world. A sense of connectedness is relational, motivating, and deeply spiritual. It is inherent in the ways we are built as social beings. All these meanings flashed in front of me as I heard that pregnant phrase, and it sent me on my own journey of revisioning addiction for myself, my clients, and my students. This new frame of reference liberated me to explore.

https://juniperpublishers.com/gjarm/GJARM.MS.ID.555565.php

https://juniperpublishers.com/gjarm/GJARM.MS.ID.555565.php

Coupling Genetic Addiction Risk Score (GARS) and Pro Dopamine Regulation (KB220) to Combat Substance Use Disorder (SUD) by Kenneth Blum (GJARM) - Juniper Publishers

Coupling Genetic Addiction Risk Score (GARS) and Pro Dopamine Regulation (KB220) to Combat Substance Use Disorder (SUD) by Kenneth Blum in Global Journal of Addiction & Rehabilitation Medicine - Juniper Publishers

 RDS conceptualization:The biological processes of reward that underlie addiction to substances and all addictive, compulsive and impulsive behaviors are the basis of the RDS conceptualization [5,6]. RDS then is a deficiency, a hypodopaminergic condition that results from some combination of genetic variations, environmental stressors, and adverse molecular effects or blunting due to prolonged substance use or behavioral habituation [7-9]. The RDS concept was developed based on animal and human research that explored the molecular biology of neurotransmission, and behavioral genetics [8,10,11]. Understanding this concept, explained in the following paragraphs, is central to treating the abnormal psychology of personality and spectrum disorders, as well as, substance and non-substance (behavioral) addictions. To feel ordinary pleasure, complex interactions of neurotransmitters regulate the dopaminergic activity of the brain in the reward center -the mesolimbic system, particularly the nucleus accumbens. Individuals, who suffer from a lack of ordinary pleasure in their lives, are predisposed to use any means; substance or behavior, to activate dopamine release, relieve stress and feel healthy pleasure [12,13].

https://juniperpublishers.com/gjarm/GJARM.MS.ID.555556.php

https://juniperpublishers.com/gjarm/pdf/GJARM.MS.ID.555556.pdf

E-Cigarettes: Risk Assessment and Possible uses for Patients with Severe COPD - An Update (GJARM) - Juniper Publishers

E-Cigarettes: Risk Assessment and Possible uses for  Patients with Severe COPD - An Update by Thomas Hering in GJARM - Juniper Publishers

Taking market data as a basis, e-cigarettes continue to enjoy major success [1]. Topulmonologists it falls to assess this development, to advise patients adequately and if appropriate to support their use. Even though for long-term risk assessment the state of information is still unsatisfactory, their use has become increasingly established. The clearest statement has been that of the Public Health Authority of the British government: this clear statement published 2015 on e-cigarettes classified their global risk as extremely positive compared to tobacco cigarettes. The risk from consumption of e-cigarettes is assessed as one twentieth of the risk of tobacco cigarettes [2]. According to this, in a hypothetical world where only e-cigarettes were consumed instead of tobacco cigarettes, after the dropping of tobacco-related morbidity and mortality – the mortality would drop by 95%. Instead of the now roughly120 thousand tobacco-related deaths eg. in Germany [3], we would be left with only 6000 “e-cigarettes-deaths.” That is according to the hypothesis, which speaks for itself

But how should pulmonologists classify their use in consultations, how should they advise patients?

Two significant arguments against e-cigarettes state that they constitute

1. A potential gateway drug for youth…
2. A potential risk of cancer from e-cigarette substances, even if it is less 

https://juniperpublishers.com/gjarm/GJARM.MS.ID.555555.php

https://juniperpublishers.com/gjarm/pdf/GJARM.MS.ID.555555.pdf