Mesenchymal Stem Cells Markers

Authored by Vasiliki E Kalodimou

In the field of regenerative medicine, basic research and preclinical studies have been conducted to overcome clinical shortcomings with the use of stem cells, mesenchymal stem cells and adipose stem cells. They are present in adult tissues, including bone marrow, umbilical cord, umbilical cord blood and adipose tissue [1]. For many years, bone marrow-derived stem cells were the primary source of stem cells for tissue engineering applications. Russian-born Alexander A. Maximow in 1924 used extensive histological findings to identify a kind of spherical precursor cell in the mesenchyme, which can grow and differentiate into Different cell types. In late 1960’s the scientists Ernest A. McCulloch and James E. Till reveal for the first time the clonal nature of bone marrow cells.

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