Thursday, October 11, 2018

Statistical Analysis of MicroRNA as Markers for Screening of Colon Cancer - Juniper Publishers


JUNIPER PUBLISHERS-BIOSTATISTICS AND BIOMETRICS OPEN ACCESS JOURNAL


Diagnostic screening can potentially reduce mortality from Colon Cancer (CC) detection because it enhances premalignant detection. The commonly used immunological Fecal Occult Blood Test (FOBTi) screening lacks sensitivity and imposes dietary restriction, resulting in decreased compliance. The Gold Standard for ColoRectal Cancer (CRC) screening "Colonoscopy" --not requiring dietary restriction-- is invasive, often accompanied by abdominal pain, has potential for complications, is not economical, and could also lead to mortality. Therefore, a noninvasive sensitive screen would be a more convenient test.



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