JUNIPER PUBLISHERS-Global Journal of Pharmacy & Pharmaceutical Sciences
Efficacy of Phytotherapy in Oral Mucosites Induced by Chemotherapy and Radiotherapy Phytotherapy in OM really work?
Authored by Braz José do
Nascimento Júnior*
Oral mucositis (OM) is a complication
of cancer therapy. Because of the associated complications, patients with OM go
through decreasing doses or until the suspension of chemotherapy treatment or
radiotherapy of head and neck until the improvement of the clinical picture,
with that, exposing them the progression of the tumor. Current treatments
produce limited results and rely on oral cryotherapy using ice, low-power laser
exposure and systemic administration of keratinocyte growth factor
(Palifermin).The use of medicinal plants and herbal medicine in the treatment
of OM is still little used, but with a tendency to expand and accept the
pharmaceutical market. We can conclude that phytotherapy is an expanding market
and that, although efficient, needs more research and better acceptance of
oncologists and other health professionals. Also some mechanisms of action are
still not well understood, therefore, studies are needed that evaluate the
long-term effects, in addition to standardized clinical protocols that prove
efficacy. An efficient natural product in the treatment of OM should have an
anti-inflammatory, bactericidal, antioxidant and healing effect on oral mucosa.
In this sense, the search for multi-herbs products can be promising, since the
plants together can have superior synergistic effects to the isolated species.
However, there are few products in the current market with this profile.
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