Long Term Test-Retest Reliability of Auditory Brainstem Response (ABR) and Middle Latency Response (MLR) by Sanjay Kumar Munjal, Naresh K Panda, and Ashis Pathak in Global Journal of Otolaryngology in Juniper Publishers
Objective:
To study the variability of auditory brainstem response (ABR) and middle
latency response (MLR) over a long term period.
Methods: 50
normal hearing subjects participated in the study. All the subjects were tested
at 3 months, 6 months and 12 months of the initial testing. The absolute
latencies and interpeak latencies of ABR waves and amplitudes & latencies
of waves Na and Pa of MLR were measured.
Results:
The Repeated measure ANOVA did not reveal any statistically significant
difference (p>0.05) between interpeak latencies of wave I-III, III-V and I-V
across the four visits. The amplitude of MLR wave Pa showed no significant
difference across four visits. However significant difference (p< 0.05)
across visits was observed for latency of wave Na.
Conclusions:
The absolute latencies of wave III & V and the interpeak latencies of waves
I-III, III-V and I-V have good test retest reliability. Reliability of wave I
however has not been established. Amplitude of wave Pa has good test retest
reliability.
Significance:
The ABR and MLR can be used as monitoring tools in a number of cases like
neurodegenerative disorders, progressive disorders of the central nervous
system.
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