Thursday, September 20, 2018

Is it Trendy to do Research on Graphene Based Materials for use in Regenerative Medicine?-Juniper Publishers

Regenerative medicine requires adequate physical supports to facilitate appropriate cellular architecture, cell polarization and guidance and the improvement of the correct differentiation processes of embryonic or adult stem cells and induced pluripotent cells. Interdisciplinary collaboration between cell biologists, physicists and engineers is required to develop and successfully achieve the objectives of this pioneering research in tissue engineering. We try, in these lines, to highlight some of the technical and methodological issues useful in the research of graphene-based nanomaterial cytocompatibility, focused on its use in biomedicine. The general goal must be increasing standardization, precision and reproducibility of cellular assays. We observed a direct relationship between the thickness and roughness of the graphene-based nanomaterials films and cell maturation. Therefore, the importance to find the most suitable thickness for inducing cell orientation, cell adherence and cell maturation. Because these types of nanomaterials are synthesized under highly controlled parameters, they might prove to be a powerful and reproducible platform for use in biomedical applications, such as tissue engineering and development of biocompatible devices.

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